Canis familiaris      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-CAF-00392
ENSCAFG00000000760
MAP3K4
2
EKS-CAF-00390
ENSCAFG00000000251
MAP3K5
3
EKS-CAF-00387
ENSCAFG00000012934
MAP3K3
4
EKS-CAF-00391
ENSCAFG00000012144
MAP3K6
5
EKS-CAF-00388
ENSCAFG00000004528
MAP3K2
6
EKS-CAF-00389
ENSCAFG00000013057
MAP3K15
7
EKS-CAF-00393
ENSCAFG00000005038
YSK4; MAP3K19
8
EKS-CAF-00394
ENSCAFG00000006917
MAP3K1