Equus caballus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-EQC-00378
ENSECAG00000008917
MAP3K3
2
EKS-EQC-00381
ENSECAG00000022251
MAP3K15
3
EKS-EQC-00382
ENSECAG00000015410
MAP3K6
4
EKS-EQC-00384
ENSECAG00000009919
YSK4; MAP3K19
5
EKS-EQC-00379
ENSECAG00000021505
MAP3K2
6
EKS-EQC-00380
ENSECAG00000024860
MAP3K5
7
EKS-EQC-00383
ENSECAG00000012724
MAP3K4
8
EKS-EQC-00385
ENSECAG00000006890
MAP3K1