Loxodonta africana      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-LOA-00396
ENSLAFG00000005303
MAP3K2
2
EKS-LOA-00395
ENSLAFG00000000588
MAP3K5
3
EKS-LOA-00402
ENSLAFG00000012768
MAP3K4
4
EKS-LOA-00401
ENSLAFG00000000985
MAP3K1
5
EKS-LOA-00400
ENSLAFG00000006042
MAP3K6
6
EKS-LOA-00398
ENSLAFG00000009429
MAP3K15
7
EKS-LOA-00399
ENSLAFG00000008034
YSK4
8
EKS-LOA-00397
ENSLAFG00000010200
MAP3K3