Oryctolagus cuniculus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-ORC-00368
ENSOCUG00000002379
MAP3K6
2
EKS-ORC-00365
ENSOCUG00000002258
MAP3K2
3
EKS-ORC-00366
ENSOCUG00000014758
MAP3K15
4
EKS-ORC-00367
ENSOCUG00000017154
MAP3K4
5
EKS-ORC-00370
ENSOCUG00000009155
MAP3K1
6
EKS-ORC-00363
ENSOCUG00000004277
MAP3K3
7
EKS-ORC-00369
ENSOCUG00000000666
YSK4
8
EKS-ORC-00364
ENSOCUG00000015434
MAP3K5