※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (14) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-MOD-00454	ENSMODG00000013669	MAPK13
2		EKS-MOD-00451	ENSMODG00000013704	MAPK14
3		EKS-MOD-00459	ENSMODG00000001074	MAPK7
4		EKS-MOD-00460	ENSMODG00000005636	MAPK11
5		EKS-MOD-00452	ENSMODG00000017722	LOC100028096
6		EKS-MOD-00458	ENSMODG00000014668
7		EKS-MOD-00463	ENSMODG00000001962	LOC100619004
8		EKS-MOD-00457	ENSMODG00000002193	MAPK8
9		EKS-MOD-00462	ENSMODG00000009057	MAPK15
10		EKS-MOD-00461	ENSMODG00000019231	NLK
11		EKS-MOD-00456	ENSMODG00000003946	MAPK9
12		EKS-MOD-00464	ENSMODG00000003819	MAPK4
13		EKS-MOD-00453	ENSMODG00000015670	MAPK3
14		EKS-MOD-00455	ENSMODG00000020770	MAPK10