※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (19) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-TEN-00578	ENSTNIG00000016527	MAPK8 (2 of 2)
2		EKS-TEN-00582	ENSTNIG00000004992	MAPK8 (1 of 2)
3		EKS-TEN-00583	ENSTNIG00000004124	NLK
4		EKS-TEN-00586	ENSTNIG00000017589	MAPK4
5		EKS-TEN-00589	ENSTNIG00000009178	MAPK15
6		EKS-TEN-00585	ENSTNIG00000009514	MAPK6
7		EKS-TEN-00587	ENSTNIG00000005520	MAPK14 (1 of 2)
8		EKS-TEN-00579	ENSTNIG00000010505	MAPK9
9		EKS-TEN-00577	ENSTNIG00000010888	MAPK13 (1 of 2)
10		EKS-TEN-00575	ENSTNIG00000008367	MAPK12 (1 of 3); MAPK12 (2 of 3)
11		EKS-TEN-00588	ENSTNIG00000004041	MAPK13 (2 of 2)
12		EKS-TEN-00573	ENSTNIG00000006906	MAPK11
13		EKS-TEN-00581	ENSTNIG00000006907	MAPK12 (3 of 3)
14		EKS-TEN-00572	ENSTNIG00000011583	MAPK3
15		EKS-TEN-00574	ENSTNIG00000015351	MAPK1
16		EKS-TEN-00580	ENSTNIG00000015202	MAPK7
17		EKS-TEN-00571	ENSTNIG00000015118	MAPK14 (2 of 2)
18		EKS-TEN-00576	ENSTNIG00000007532	MAPK10
19		EKS-TEN-00584	ENSTNIG00000003221