Bos taurus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-BOT-00389
ENSBTAG00000019855
MAP3K15
2
EKS-BOT-00386
ENSBTAG00000008151
MAP3K3
3
EKS-BOT-00390
ENSBTAG00000020079
MAP3K4
4
EKS-BOT-00391
ENSBTAG00000010254
MAP3K6
5
EKS-BOT-00392
ENSBTAG00000014409
YSK4
6
EKS-BOT-00393
ENSBTAG00000013790
MAP3K1
7
EKS-BOT-00388
ENSBTAG00000004216
MAP3K2; Bt.92459
8
EKS-BOT-00387
ENSBTAG00000009065
MAP3K5; BT.31917