※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (13) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-CAP-00504	ENSCPOG00000013605	MAPK10
2		EKS-CAP-00496	ENSCPOG00000013948	MAPK9
3		EKS-CAP-00498	ENSCPOG00000013041	MAPK1
4		EKS-CAP-00501	ENSCPOG00000013318	MAPK15
5		EKS-CAP-00500	ENSCPOG00000001093	NLK
6		EKS-CAP-00492	ENSCPOG00000014893	MAPK14
7		EKS-CAP-00495	ENSCPOG00000014859	MAPK12
8		EKS-CAP-00494	ENSCPOG00000014626	MAPK13
9		EKS-CAP-00503	ENSCPOG00000010565	MAPK4
10		EKS-CAP-00502	ENSCPOG00000010022	MAPK6
11		EKS-CAP-00493	ENSCPOG00000003253	MAPK3
12		EKS-CAP-00497	ENSCPOG00000015571	MAPK8
13		EKS-CAP-00499	ENSCPOG00000027276	MAPK7