※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (12) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ORC-00436	ENSOCUG00000007543	MAPK12
2		EKS-ORC-00439	ENSOCUG00000002873	MAPK8
3		EKS-ORC-00435	ENSOCUG00000014799	MAPK13
4		EKS-ORC-00446	ENSOCUG00000013016	MAPK4
5		EKS-ORC-00444	ENSOCUG00000017881	MAPK15
6		EKS-ORC-00438	ENSOCUG00000010663	MAPK10
7		EKS-ORC-00440	ENSOCUG00000013716	MAPK3
8		EKS-ORC-00441	ENSOCUG00000013692	MAPK1
9		EKS-ORC-00445	ENSOCUG00000012189	MAPK6
10		EKS-ORC-00437	ENSOCUG00000015542	MAPK9
11		EKS-ORC-00442	ENSOCUG00000015154	MAPK7
12		EKS-ORC-00443	ENSOCUG00000007764	NLK