Macaca mulatta      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-MAM-00388
ENSMMUG00000018318
MAP3K6
2
EKS-MAM-00392
ENSMMUG00000018568
MAP3K2
3
EKS-MAM-00389
ENSMMUG00000006143
MAP3K4; EGK_15488
4
EKS-MAM-00390
ENSMMUG00000017121
YSK4
5
EKS-MAM-00387
ENSMMUG00000017339
MAP3K15
6
EKS-MAM-00391
ENSMMUG00000012387
MMU.9865; MAP3K1
7
EKS-MAM-00385
ENSMMUG00000016751
MAP3K3
8
EKS-MAM-00386
ENSMMUG00000016376
MAP3K5