※ STKR family introduction

    STKR are serine/threonine kinase receptor comprising two subfamily, TGFb receptors and activin receptors. TGFb receptors contain different isoforms which are homo- or heterodimeric. The mediate the interaction between ligand and receptor. TGFb receptors are expressed in diverse tissues, including heart, liver, kidney, brain and testes. TGFb receptor can be further classified into three subclasses from type1 to type3. Abnormal expression of TGFb receptor leads to renal fibrosis which will result in kidney disease. Diabetes is also found to be associated with TGFb receptor (1). Another subfamily is activin receptors, which are characterized by its feature to bind activin. The activin receptors contain a transmembrane domain and a hydrophilic Cys-rich ligand-binding domain (2).

Reference
1. Wikipedia annotation: TGF beta receptors
2. Wikipedia annotation: Activin receptor

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ORN-00370	ENSONIG00000016136
2		EKS-ORN-00361	ENSONIG00000016072	BMPR1A
3		EKS-ORN-00357	ENSONIG00000008959	ACVR1
4		EKS-ORN-00354	ENSONIG00000008966	ACVR1C
5		EKS-ORN-00353	ENSONIG00000009648	TGFBR1
6		EKS-ORN-00358	ENSONIG00000019071	ACVR1B (2 of 2)
7		EKS-ORN-00369	ENSONIG00000019673	TGFBR2 (1 of 2)
8		EKS-ORN-00356	ENSONIG00000014932	BMPR1B (1 of 2)
9		EKS-ORN-00359	ENSONIG00000014017	BMPR1B (2 of 2)
10		EKS-ORN-00368	ENSONIG00000013213	BMPR2 (1 of 2)
11		EKS-ORN-00364	ENSONIG00000018510	ACVR2B (2 of 2)
12		EKS-ORN-00367	ENSONIG00000013839	TGFBR2 (2 of 2)
13		EKS-ORN-00360	ENSONIG00000001235	LOC100711913
14		EKS-ORN-00362	ENSONIG00000012120	ACVRL1
15		EKS-ORN-00355	ENSONIG00000012123	ACVR1B (1 of 2)
16		EKS-ORN-00371	ENSONIG00000005789	BMPR2 (2 of 2)
17		EKS-ORN-00365	ENSONIG00000005816	ACVR2A (2 of 2)
18		EKS-ORN-00366	ENSONIG00000017364	ACVR2B (1 of 2)
19		EKS-ORN-00363	ENSONIG00000012275	ACVR2A (1 of 2)
20		EKS-ORN-00372	ENSONIG00000012464	AMHR2