Homo sapiens      CMGC      CDK

※ CDK family introduction

    CDK (Cyclin-dependent kinase) belong to CMGC family. CDKs are ser/thr protein kinases that play an important in regulation of a number of cellular processes in eukaryotes. CDKs are also characterized by its feature that they require an activation subunit called cyclin (1).

Reference
1. Casteel, D.E., Zhang, T., Zhuang, S. and Pilz, R.B. (2008) cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity. Cell Signal, 20, 1392-1399. PMID: 18450420


There are 21 genes.  Reviewed (19 or Unreviewed (2

No.StatusEKPD IDGene IDGene Name
1
EKS-HOS-00061
ENSG00000102225
PCTK1; CDK16
2
EKS-HOS-00064
ENSG00000008128
CDK11A; CDC2L2, CDC2L3, PITSLREB
3
EKS-HOS-00060
ENSG00000059758
CDK17; PCTK2
4
EKS-HOS-00071
ENSG00000105810
CDKN6; CDK6
5
EKS-HOS-00057
ENSG00000250506
CDKN3; CDK3
6
EKS-HOS-00072
ENSG00000138395
ALS2CR7, PFTK2; CDK15
7
EKS-HOS-00066
ENSG00000167258
CRK7, CRKRS, KIAA0904; CDK12
8
EKS-HOS-00070
ENSG00000262841
CDK7
9
EKS-HOS-00058
ENSG00000170312
CDK1; CDC2, CDC28A, CDKN1, P34CDC2
10
EKS-HOS-00076
ENSG00000155111
CDK19; CDC2L6, CDK11, KIAA1028
11
EKS-HOS-00073
ENSG00000132964
CDK8
12
EKS-HOS-00069
ENSG00000185324
CDK10
13
EKS-HOS-00063
ENSG00000248333
CDK11B
14
EKS-HOS-00067
ENSG00000136807
CDC2L4, TAK; CDK9
15
EKS-HOS-00056
ENSG00000123374
CDKN2; CDK2
16
EKS-HOS-00062
ENSG00000117266
CDK18; PCTK3
17
EKS-HOS-00075
ENSG00000156345
CCRK, CDCH; CDK20
18
EKS-HOS-00068
ENSG00000058091
KIAA0834, PFTK1; CDK14
19
EKS-HOS-00059
ENSG00000164885
CDKN5; CDK5
20
EKS-HOS-00065
ENSG00000065883
CDC2L, CDC2L5, CHED, KIAA1791; CDK13
21
EKS-HOS-00074
ENSG00000135446
CDK4